Organische ChemieFragen und Antworten zur Chemie der Kohlenwasserstoffe. Hier kann alles von funktionellen Gruppen
über Reaktionsmechanismen zu Synthesevorschriften, vom Methan zum komplexen Makromolekül diskutiert werden.
Knochel et al. proposed that LiCl increases the reactivity of Turbo-Grignard compounds RMgCl·LiCl (R = alkyl, aryl or vinyl) by giving the reactive bimetallic monomer a magnesiate character in sense of a solvent separated ion pair (SSIP) [Li(THF)4]+ [RMg(THF)Cl2]−.[1][11] In case of the above mentioned Turbo-Hauser bases where the alkyl group of a Grignard is replaced by an amido group (R = R'2N−) this hypothesis could not be confirmed because no SSIP [Li(THF)4]+ was detectible.
LiCl has been shown to increase solubility of RZnX reagent as well. Without LiCl, organozinc reagent remains on surface of zinc particle. With LiCl organozinc reagent forms a RZnX-LiCl complex, which is more soluble in THF.